Synthesis and characterization of a cobalt complex bearing a chiral nitrogen-based ligand.
DOI:
https://doi.org/10.55632/pwvas.v90i1.421Keywords:
OrganometallicsAbstract
Hydrogenation reactions are used to create essential molecules in today’s pharmaceutical, petrochemical, and agricultural industries. Single enantiomer products are desirable and often developed using asymmetric hydrogenation reactions, especially important for drug synthesis in the pharmaceutical industry. Asymmetric hydrogenation reactions currently utilize catalysts made from expensive and toxic metals, such as ruthenium, rhodium, and iridium, and are usually supported by phosphine ligands. Synthesis of an asymmetric catalyst based on a first row transition metal would be advantageous. In addition, chiral nitrogen-based ligands provide an opportunity to investigate a relatively underexplored area of hydrogenation chemistry. Thus, efforts toward a cobalt complex supported by a chiral nitrogen-based ligand, (R,R)-2,6-bis[1-(N-piperidinyl)ethyl]pyridine, are underway. Ligand synthesis, characterized by NMR spectroscopy, and initial reactions with cobalt will be discussed.
Downloads
Published
How to Cite
Issue
Section
License
Proceedings of the West Virginia Academy of Science applies the Creative Commons Attribution-NonCommercial (CC BY-NC) license to works we publish. By virtue of their appearance in this open access journal, articles are free to use, with proper attribution, in educational and other non-commercial settings.